The fundamental principle, in my mind, is that people have a right to reproduce. That is probably the most fundamental right there is, in my opinion...the right, as a couple, to push your genes into the next generation.
The fact that we as a society have taken steps to stop natural selection?...that is on us as a society.
I would rather (i) return to allowing natural selection (cutting societal benefits / eliminating equality of status, and increasing freedom / equality of opportunity), and (ii) allowing procreation as a fundamental right (and allow the strong to give it a go on their own to survive and procreate). That is a natural society that will improve over time.
I would oppose (i) preventing natural selection, while (ii) preventing procreation. That is an evil society that will stagnate and devolve into tyranny.