What Putin said is warning Europe. Russia will attack any airfield that those F-16 use for the war. He just made it clear that such attacking doesn't mean Russia attacks Europe.
F-16 is too delicate, needs a good airport/runway. A damaged runway even a dirty runway will affect its mission.
Putin gave warning in advance in case any country will provide airports for Ukraine's F16. Not to mention in air to air fight Russia's jets have much better radars than F-16's out of date radar. Russia pilots can see F-16 before F-16 pilots see Russia's Mig-31, Mig-35 or Su-35.
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