After reading this excerpt from that article YOU linked...you'll see that, while everyone would love for any drug...even Ivermectin...to be a "WIN" against Malaria... the data shows it isn't.
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In the 6 months following the first dose, there were 1292 cases of malaria in children in the albendazole clusters and 1048 in the ivermectin clusters, a 26% reduction in incidence. “Ivermectin has been talked about for a long time as having potential against malaria, but this is the first major … high-quality evidence for such impact,” Okumu says.
It’s important that the drug appears to help reduce malaria in school-age children, says Okumu, who is from Kenya. That group often profits less from insecticide-treated bed nets—another key malaria prevention tool—because unlike adults and small children, they often don’t sleep in beds that can be covered by nets. "In my case, when I was a kid, most of my school-aged years I slept on floor mats made of reeds, often without a mattress and obviously not a place where [bed nets] are that usable," Okumu adds.
But Last says 26% is not very impressive. “I think there's questionable public health benefit in something so small,” she says. And the strategy has drawbacks, she notes. For example, ivermectin cannot currently be given to pregnant women or young children, which means mosquitoes don’t get exposed to the drug every time they bite someone.
Previous studies where ivermectin was widely given have not even been as compelling as the new finding. The first attempt of the strategy, conducted in eight villages in Burkina Faso in 2015, did find that five additional doses of ivermectin could reduce malaria in children compared with one dose of ivermectin and albendazole, but the trial was small and researchers have questioned how statistically valid the results are. A larger follow-up study in Burkina Faso in 2019 and 2020 showed no significant reduction of malaria in children. Last’s own study in Guinea-Bissau, published in April, showed no effect on malaria incidence at all.
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