Assuming Wimbush plays, the one part of the offense that is better with him in the game is the zone read. Teams have to account for him on the edge which opens up the middle of the field. It's why Josh Adams had so many long runs last year and Dexter had a couple similar ones against a very good FSU front 7.
If ND avoids TOs and ST miscues they should be fine even without Book.
Edit: Sounds like Book should be back. Even better.
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