I have ND buds from Michigan and they absolutely despise Michigan. Trauma from childhood taunts and proximity to their arrogant fanbase.
Michigan fans have a displaced sense of the program's standing in college football. My dislike for them starts with Fielding Yost and extends to their multiple claimed bogus natty's. Their inferiority complex to ND was on full display during Bo's infamous 'to hell with ND' rant. And there can be no question that they cheated this year, so there's that.
Like you, there are others I dislike more. USC will always be my most disliked opponent, followed by Miami and Florida State.
EDIT: typo
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